| Programma | |||||||
| Datum | Tijd | Thuis | Score | Bezoeker | Verslag | ||
| 25/09/2021 | 18:00 | Aqua Sport Brugge A | - | Aqua Sport Brugge B | |||
| 2/10/2021 | 17:15 | Antwerpen 3 | - | Aqua Sport Brugge B | |||
| 9/10/2021 | 18:00 | Aqua Sport Brugge B | - | Kortrijk 2 | |||
| 15/10/2021 | 21:00 | Blankenberge | - | Aqua Sport Brugge B | |||
| 23/10/2021 | 18:00 | Aqua Sport Brugge B | - | Dendermonde | |||
| 6/11/2021 | 21:30 | Aalst B | - | Aqua Sport Brugge B | |||
| 13/11/2021 | 18:00 | Aqua Sport Brugge B | - | Tielt B | |||
| 21/11/2021 | 10:00 | Aqua Sport Brugge B | - | Aqua Sport Brugge A | |||
| 24/11/2021 | 21:00 | Aqua Sport Brugge B | - | Antwerpen 3 | |||
| 4/12/2021 | 20:00 | Kortrijk 2 | - | Aqua Sport Brugge B | |||
| 11/12/2021 | 18:00 | Aqua Sport Brugge B | - | Blankenberge | |||
| 18/12/2021 | 20:30 | Dendermonde | - | Aqua Sport Brugge B | |||
| 5/02/2022 | 18:00 | Aqua Sport Brugge B | - | Aalst B | |||
| 13/02/2022 | 17:30 | Tielt B | - | Aqua Sport Brugge B | |||
H2Opolo.be