| Team | M | M+ | M= | M- | D+ | D- | DV | Pnt | |
| 1 | Gentse | 14 | 9 | 0 | 5 | 182 | 148 | 34 | 27 |
| 2 | Hasselt | 14 | 9 | 0 | 5 | 149 | 131 | 18 | 27 |
| 3 | Antwerpen 2 | 14 | 8 | 1 | 5 | 157 | 138 | 19 | 25 |
| 4 | Calypso | 14 | 8 | 1 | 5 | 182 | 150 | 32 | 25 |
| 5 | Brussels | 14 | 7 | 0 | 7 | 157 | 159 | -2 | 21 |
| 6 | Waregem | 14 | 6 | 1 | 7 | 144 | 181 | -37 | 19 |
| 7 | Aalst | 14 | 5 | 1 | 8 | 146 | 134 | 12 | 16 |
| 8 | Bergen | 14 | 1 | 2 | 11 | 124 | 200 | -76 | 5 |
| Programma | |||||
| Alle Wedstrijden en Uitslagen Tweede Divisie - seizoen 2021-2022 | |||||
| Datum | Tijd | Thuis | score | Bezoeker | |
| Vorige Week | |||||
| Volgende Week | |||||
| ZNA | AZSC2 | CCM | RBP | SCC | KGZV | HZS | WPW | |
| Aalst | 11-10 | 20-6 | 9-10 | 12-8 | 10-12 | 4-5 | 9-10 | |
| Antwerpen 2 | 6-6 | 12-6 | 16-11 | 13-8 | 9-8 | 8-6 | 13-9 | |
| Bergen | 11-10 | 6-10 | 8-10 | 12-12 | 8-18 | 9-11 | 12-12 | |
| Brussels | 10-12 | 13-9 | 16-9 | 15-16 | 12-9 | 7-8 | 10-9 | |
| Calypso | 12-11 | 14-11 | 23-9 | 11-13 | 8-9 | 15-8 | 20-6 | |
| Gentse | 11-14 | 15-12 | 20-11 | 22-14 | 9-10 | 12-10 | 19-10 | |
| Hasselt | 12-8 | 15-11 | 17-9 | 9-6 | 12-9 | 8-9 | 19-10 | |
| Waregem | 11-10 | 10-17 | 9-8 | 12-10 | 10-16 | 12-9 | 14-9 |
H2Opolo.be